Sunday, March 05, 2006

Diluting a Disease: Could Homeopathy Stop The Avian Flu?

In 1918 A vicious strain of flu spread to every populated continent, snuffing out lives faster than coffin makers could supply caskets. The Spanish flu killed as many as 50 million people over two years. People who were perfectly healthy when they woke up in the morning could be dead by nightfall. Medical classes were cancelled so that students could serve as doctors and nurses. In Europe, military strategists on all sides of World War I scrambled to redraw battle plans for lack of healthy soldiers.

Surrounded by death and reduced to simply comforting patients with aspirin, a desperate doctor in Pittsburgh asked a nurse whether she knew a better way to save lives. The nurse, who had worked with homeopaths, urged the skeptical doctor to switch to their simple remedies, which she had seen save countless lives.

According to the late homeopathic historian and authority Julian Winston, a victim of the Spanish flu treated by a conventional doctor had only a 70% chance of surviving; homeopaths saved 99% of their patients. Now a number of modern-day homeopaths believe they can help fight another pandemic -- a rare bit of hopeful news given that neither the mainstream medical establishment nor the pharmaceutical industry had found a way to counter H5N1, the virus that causes avian flu.

German physician Samual Hahnemann discovered homeopathy 200 years ago when he found that cinchona bark containing quinine, then the best treatment for malaria, caused all the symptoms of malaria in a healthy person. After experimenting with more than 200 substances, he concluded that like cures like. Give someone with a runny nose a homeopathic solution of onion, that pungent veggie that normally causes a runny nose, and it strengthens the body in just the right way to heal. If you're suffering from insomnia, a homeopath will give you a controlled dose of caffeine-like substance.

Homeopaths dilute substances in double-distilled water, vigorously shake the mixture, and then dilute it again, explains homeopath Dana Ullman. They repeat this over and over until it's unlikely that a single moledule of the original substance remains, and then deliver what's left in a pill or liquid. No one knows exactly why this works, but homeopaths posit that water retains the energy of a substance and delivers a message to the body. (Ullman likens it to rubbing a magnet on a piece of metal to transfer the magnetic properties.)

Because of its success in treating the era's epidemics, homeopathy enjoyed its greatest popularity during the 19th century. Just before the American Medical Association was founded as an alternative to the American Institute of Homeopathy, there were 22 homeopathic medical schools in the United States, including at Boston University and Stanford. Today, the method is most popular in England, where 40% of conventional doctors refer patients to homeopaths.

Countless conventional studies, including one published last summer in the British medical journal The Lancet, have concluded that homeopathic remedies are no more reliable than placebos -- cold comfort in the face of a deadly virus. The French Society of Homeopathy, however, found in a 1998 survey that 90% of those who used a homeopathic solution called Influenzinum were able to avoid a common flu bug. For those already laid up with the flu, at least three separate studies favor homeopathic treatments over using a placebo.

Some mainstream doctors, like Christian Sandrock of the University of California-Davis Medical Center, are willing to consider this evidence but still cautions patients against relying on it as a cure-all. And some mainstream doctors still stereotype homeopaths as con artists or quacks. But even homeopathy's harshest critics don't accuse practitioners like Ullman of peddling harmful substances, so there's a powerful argument to pursue the remedy further.

The standard flu vaccine requires specially cultivated chicken eggs, infected with a specific strain of virus that can be grown only after it is identified, which is why scientists must wait until H5N1 mutates into a human-t0-human bug. Once this happens it will be difficult to produce vaccine fast enough (one dose often requires its own egg). And even if a number of non-existent pharmaceutical facilities sprang up to instantaneously produce vats of vaccine, scientists aren't sure whether host eggs could survive long enough to be harvested.

In the short term, the U.S. and Asian governments have pinned their hopes on Tamiflu, an antiviral drug (not a vaccine) meant to seize influenza inside a victim's cells. It works in petri dishes, but, according to the maker's website, its effectiveness in humans has not been established. Even if Tamiflu proved deadly to the virus, homeopaths point out that the antiviral could, as antibiotics have in the past, cause patients to build up resistance or spur diseases to mutate into more powerful strains, constantly upping the ante. Ullman goes so far as to argue that people who take Tamiflu "are posing a public health threat."

Homeopaths prescribe remedies according to symptoms, so they already have the ability to study the disease in patients without worrying about which strain of what virus is the culprit. Homeopathic treatments are cheaper and easier to produce than a standard vaccine because they're made from natural substances and pure water. And since most remedies aren't patented, progress isn't hindered by squabbles over intellectual property rights. Best of all, homeopathy is about strengthening the body instead of targeting the bug, so patients don't become unwitting vessels for a mutated virus.

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